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Adaptive-glasses wavefront sensorless full-field OCT for high-resolution retinal imaging over a wide field-of-view

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Document pages: 8 pages

Abstract: The highest three-dimensional (3D) resolution possible in in-vivo retinalimaging is achieved by combining optical coherence tomography (OCT) andadaptive optics (AO). However, this combination brings important limitations,such as small field-of-view and complex, cumbersome systems, preventing so farthe translation of this technology from the research lab to clinics. In thisLetter, we introduce an approach that avoids these limitations by using amulti-actuator adaptive lens just in front of the eye, in a technique we callthe adaptive-glasses wavefront sensorless approach. We implemented thisapproach on our compact full-field OCT (FFOCT) retinal imager withoutincreasing its footprint or optical complexity. The correction of ocularaberrations through the adaptive-glasses approach increased the FFOCTsignal-to-noise ratio and enabled us to image different retinal layers with a3D cellular resolution in a 5° $ times$ 5° field-of-view, withoutapparent anisoplanatism.

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