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Correlates of Hepatitis B Virus Infection among Antenatal Clinic Attendees of Volta Regional Hospital, Ho, Volta Region, Ghana

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Document pages: 14 pages

Abstract: Hepatitis B virus (HBV) infection remains a global health problem. Withabout 380 million chronic carriers of the HBV virus, there are over two millionglobal deaths annually. Ghana is among the high endemic countries in Africa,with HBV prevalence ranging from 4.8 to 12.3 in the general population, 10.8 to 12.7 in blood donors and about 10.6 in antenatal clinic (ANC) attendees.The main objectives of this study were to test how socioeconomic factors, riskybehaviors, knowledge and awareness of HBV infection correlate with actual HBVstatus among antenatal clinic attendees and to determine the predictors of HBVtesting among ANC attendees. The study employedrandom sampling technique to sample 500 pregnant women, at mothers’ clinic of Volta Regional Hospital, Ho, Ghana. A structured questionnaire wasused to collect information on socio-demographic characteristics, Hepatitis Bstatus, possible risk factors, awareness and knowledge levels of HBV infection. Cross tabulation and the chi-square (χ2)statistic were used to determine statistical independence or association ofstudy variables. Kruskal-Wallis testwas applied to test for the differences in HBV knowledge scores across HBVstatus and levels of HBV awareness; and the binomial regression model was usedto determine the predictors of HBV testing among ANC attendees. It is evidentthat age, religion, ethnicity, educational level, blood transfusion, number ofblood transfusions, gravidity, parity, awareness of HBV and monthly income wereassociated with HBV status. Results of the Binomial Logistic Regression modelindicate that Age (p = 0.03),Education level (p = 0.04), Religion(p = 0.04), Ethnicity (p = 0.00) and Blood transfusion (p = 0.04) were significant (p 0.05)predictors of HBV testing. Knowledge of HBV status enables patients to seekearly treatment, facilitates referral for social support and counseling. We recommend that the Ministry of Healthshould carry effective education on HBV and its prevention for women ofchild-bearing age.

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