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Treatment outcome and related factors of tuberculosis in Ethiopia University Hospital

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Document pages: 10 pages

Abstract: Background tuberculosis is still a major global health problem. It causes ill health among millions of people every year, and ranks as the main cause of death in the world together with human immunodeficiency virus (HIV). To assess the outcome of TB treatment and identify factors associated with TB treatment outcome. method. A five-year retrospective cross-sectional study was used to collect data through medical record review. The data were analyzed by SPSS version 16, and binary and multiple logistic regression methods were used. In the final model, values less than 0.05 were considered statistically significant. Results among 1584 patients with pulmonary tuberculosis (882 men and 702 women), including all age groups, 60.1 obtained successful treatment results and treatment9.9 had unsuccessful outcome. In the final multivariate logistic model, the odds of unsuccessful treatment outcome was higher among patients of weight category 30–39.9 kg (AOR = 1.51, 95 CI: 1.102–2.065) and smear negative pulmonary TB (AOR = 3.204, 95 CI: 2.277–4.509) and extrapulmonary TB (AOR = 3.175, 95 CI: 2.201–4.581) and retreatment (AOR = 6.733, 95 CI: 3.235–14.013) and HIV positive TB patients (AOR = 1.988, 95 CI: 1.393–2.838) and unknown HIV status TB patients (AOR = 1.506, 95 CI: 1.166–1.945) as compared to their respective comparison groups. Conclusion. In this study, high proportion of unsuccessful treatment outcome was documented. Therefore emphasis has to be given for patients with high risk of unsuccessful TB treatment outcome and targeted interventions should be carried out.

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