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Potential biodynamic Tetraaza macrocycles and their applications

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Document pages: 17 pages

Abstract: Fourteen to eighteen membered tetraazamacrocyclic ligands n4ttd1 – n4ttd4 were synthesized by the following methods:Dn)] (where n = 1 - 8)has been established on the basis of chemical composition. To assess the growth inhibiting potential of theligands and their manganese (II) complexes biological screening have been undertaken. The testicularmorphology, testicular sperm density, sperm motility, density of cauda epididymal spermatozoa and fertilityin mating trials and biochemical parameters of reproductive organs with ligands and their correspondingcomplexes, in vivo have also been described in the this communication.

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