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Chondroitin sulfate C stabilized submicron calcium oxalate suspension may be an effective method to prevent stone formation

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Document pages: 9 pages

Abstract: The effects of chondroitin sulfate C (c6s) on the size, aggregation, precipitation and zeta potential of submicron calcium oxalate monohydrate (COM) and calcium oxalate dihydrate (COD) microcrystals (average particle size about 330) were studied by X-ray diffractometer, nano particle zeta potential analyzer, UV spectrophotometer and scanning electron microscope, Then the results are compared with those of micron crystals. C6s inhibited the transformation of COD to com and the aggregation of COM and COD crystals; It also reduces their sedimentation rate and improves their stability in aqueous solution. The smaller the size of COD crystallite, the easier it is to convert to com. The stability of submicron cod is worse than that of micrn-grade crystals. C6S can inhibit the formation of calcium oxalate stones.

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