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Effects of curcumin copper (ⅱ) and curcumin zinc (ⅱ) complexes on amyloid β- Inhibitory effect of peptide on fibrillation

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Document pages: 8 pages

Abstract: It has been synthesized β- Curcumin monopeptide and β- Curcumin complexes and their effects on β- Curcuminization and β- Effects of curcumin. FTIR spectra and atomic force microscopy (AFM) observations showed that the complex could inhibit the transfer of oligomers with low structure to oligomers with high content β- The transformation of fibrils in tablets can be used as a seed factor for further fibrillation. Compared with curcumin, the inhibitory effect of metal complexes on peptidogenic fibrosis was also improved.

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