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Protonation equilibrium of bioactive ligands in mixed organic solvents

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Document pages: 18 pages

Abstract: The protonation equilibrium of bioactive ligands such as amino acids, peptides, DNA components and amino acid esters in non-aqueous media is reviewed. The relationship between the equilibrium concentration of proton ligand formation and pH value was studied. In addition, the thermodynamics related to protonation equilibrium is also discussed.

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