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Construction of zinc oxide antibacterial agents with different morphological structures

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Document pages: 20 pages

Abstract: Through sol gel and hydrothermal technology, nano Zinc Oxide has been successfully applied to particle, rod and tube nanostructures. Different morphologies and structures were obtained by changing different preparation parameters, such as reaction temperature, time and stabilizer. The effects of microwave annealing on the crystallinity, surface area and morphology of ZnO were monitored by XRD, bet and SEM. The antibacterial activity of zinc oxide produced in nanotube structure against four different multi drug resistant bacteria: Gram-positive bacteria (Staphylococcus aureus and Bacillus subtilis) and Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa). The activity of the prepared nano ZnO was determined by B disc diffusion technique and the results revealed that ZnO nanotubes recorded high activity against the studied strains due to their high surface area equivalent to 17.8 m2 g. The minimum inhibitory concentration (MIC) of ZnO nanotubes showed that the low concentrations of ZnO nanotubes could be a substitution for the commercial antibiotics when approached in suitable formula. Although the annealing process of ZnO improves the degree of material crystallinity, however, it declines its surface area and consequently its antimicrobial activity.

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