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Analysis of adsorption behavior of titanium dioxide nanoparticles by quartz crystal microbalance sensor

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Document pages: 10 pages

Abstract: We studied the adsorption of albumin and fibronectin on a quartz crystal microbalance (QCM) sensor modified by titanium dioxide nanoparticles (TNS -). Ti QCM sensor was prepared by reactive magnetron sputtering. A thin layer of Ti was deposited on the QCM sensor. Then, the sensor was alkali modified with NaOH at room temperature to prepare titanium dioxide nanoparticles. Scanning probe microscopy, X-ray photoelectron spectroscopy and scanning electron microscopy were used to study the surface topology and chemical composition of each sensor. The titanium oxide film of TNS has a nodular structure, with a thickness of 13   and 0.5 nm on QCM sensor. In addition, QCM measurements showed that the amount of albumin and fibronectin adsorbed on TNS was significantly higher than that of titanium.he NaOH treatment of titanium modified the sensor surface and improved the adsorption behaviors of proteins related to the initial adhesion of bone marrow cells. Therefore, we concluded that TNS improves the initial adhesion between the implant materials and the surrounding tissues.

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