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Azacitidine Causing Generalised Skin Rash: A Rare Side Effect

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Document pages: 5 pages

Abstract: Azacitidine is one of the hypomethylating agents used for management of myelodysplastic syndrome (MDS). A 68-year-old male was diagnosed as a case of MDS Excess Blast-2 and was started with subcutaneous azacitidine injection. After two days, he developed erythematous maculopapular lesions of varying sizes over the trunk and extremities associated with itching. While toxic reaction at the injection site is common, allergic reaction is not widely known. It requires attention to systemic skin reactions because the incidences are likely to increase with the increasing use of Azacitidine.

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