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Processed Exudate of Pathogen Can Kill Wild Pathogens: Successful In Vitro Application of Newly Synthesized Novel Antimicrobial Therapeutic against Multiple Human Pathogens & Plant Pathogens

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Document pages: 4 pages

Abstract: Rhizoctonia solani is a plant pathogenic fungus. In this study synthesis of an antimicrobialtherapeutic agent is carried out using cell free culture supernatant of Rhizoctonia solani. The synthesizedtherapeutic or biomedicine was analyzed using UV-VIS spectrophotometry which showed theappearance of SPR centered near about 520nm. The therapeutic agent can be cadmium sulphidenanoparticles (CdSNPs). Antimicrobial assay of this newly synthesized therapeutic agent was performedagainst four prokaryotic pathogens which are usually human pathogen & seven eukaryotic pathogenswhich are mainly plant pathogen. The newly synthesized therapeutic agent revealed their effectiveantibacterial activity against Bacillus subtilis MTCC430 by forming 0.8 mm clear zone, against Bacilluscereus MTCC441 by forming 1 mm clear zone, against Vibrio parahaemolyticus by forming 0.9 mm clearzone. MIC has been recorded as 111.12 μg ml for B. subtilis MTCC430, 107.11 μg ml for B. cereusMTCC441 & 79.38 mg ml for Vibrio parahaemolyticus. The newly synthesized therapeutic is alsorevealed positive activity against Sclerotinia sclerotinum & Alternaria alternata.

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